Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/192958269?client_source=feed&format=rss
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Sunday, January 29, 2012
Saturday, January 28, 2012
HBT: Cuban out of running to buy Dodgers
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ZTE Score (Cricket Wireless)
How does this sound to you: $65 per month for unlimited talk, text, Web, and music with no contract. Pretty good, right? The catch: you're stuck accessing it all with a mediocre Android smartphone. That's the dilemma you face with the ZTE Score ($69.99) for Cricket Wireless. It's a great deal, in need of a better phone.
Design, Call Quality, and Plan Pricing
The ZTE Score measures 4.4 by 2.5 by .5 inches (HWD) and weighs 4.5 ounces. The front and back are made of glass, with a thick ring of matte black plastic separating the two. It looks sharp, and its size makes it comfortable to hold and use. The 3.5-inch touch screen sports 320-by-480-pixel resolution, which is standard for budget Android phones. The onscreen keyboard is a bit small, but I didn't have any trouble typing on it.
The Score is a triband EV-DO Rev A (850/1700/1900 MHz) device with 802.11b/g Wi-Fi. It connected to my?WPA2-encrypted Wi-Fi network?without a problem, but reception on Sprint's network here in New York was shaky and voice quality is mixed. Cricket uses its own network in about a third of the country, and Sprint's network in the rest.
Volume is low in the earpiece, and voices sounded thin and robotic. Calls made with the phone are easy to understand, but again voices sounded computerized and background noise cancellation was poor. Calls sounded better through a Jawbone Era?Bluetooth headset ($129, 4.5 stars) and voice dialing worked fine over Bluetooth without training. The speakerphone sounds fine, but its volume is far too low to use outside. Battery life was on the short side at 4 hours, 49 minutes of talk time.
Cricket offers unlimited smartphone plans with its downloadable Muve Music service for $65/month, which is more affordable than all the major carriers but still more expensive than Boost Mobile's $55/month smartphone plan, which can actually reduce to $40/month as you pay your bills on time. But that extra $10 per month for unlimited music is an attractive option, and one that will likely be a deciding factor for many users. MetroPCS recently started offering a similar plan where $60 per month will get you unlimited talk, text, and Web, along with unlimited music via Rhapsody. (Without Rhapsody, that plan costs $50.)
OS, Multimedia, and Conclusions
The Score runs Android 2.3.4 (Gingerbread). There's no word on an update to Android 4.0 (Ice Cream Sandwich), and don't count on one. ZTE has added some light customizations to Android, but they're mostly visual. There are five home screens you can swipe between, and the phone feels surprisingly responsive given its outdated 600 MHz Qualcomm MSM7627 processor.
You get all of usual perks of Android, which include native support for Microsoft Exchange; free Google Maps Navigation for voice-enabled, turn-by-turn GPS directions; a solid?WebKit browser; and compatibility with more than 300,000 third-party apps in the Android Market.
There's a side-mounted microSD card slot on the right side of the phone. Slip the included card out and you'll notice it says "3GB Muve Music, 1GB Your Space." That means the card is divided into two partitions, and the Muve partition is hidden and encrypted. You can only see the extra 1GB on a PC. You also can't use standard MicroSD memory cards for Muve. Cricket doesn't yet sell the special cards the phone accepts, though replacement 4GB and 8GB cards are in the works.
In addition to the 1GB on the microSD card, there's also 110MB of free internal storage. Music sounded fine through both wired earbuds and?Altec Lansing Backbeat?Bluetooth headphones ($99, 3.5 stars), though bass response was somewhat lacking. Outside of Muve, the Score was able to handle AAC, MP3, OGG, and WAV music files. DivX, H.264, and MP4 video files played back smoothly at resolutions up to 800-by-480.
The 3.2-megapixel camera is weak. Test photos look average outdoors, but photos taken inside appear soft and blurry, almost hazy, like a scene from a bad music video. The camera also records video at a low 352-by-288-pixel resolution. Videos are tiny and grainy, and play back at a choppy 12 frames per second indoors, and 15 frames per second outside.
Source: http://feedproxy.google.com/~r/ziffdavis/pcmag/~3/Eob_LmyH7us/0,2817,2399408,00.asp
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Friday, January 27, 2012
Avastin's Failure in Breast Cancer: New Study May Explain Why It Happened (LiveScience.com)
A new study may explain why the cancer drug Avastin hasn't worked in the treatment of breast cancer patients. Although the drug stops tumor growth for a short time, it often leads to more invasive tumors in the long run.
The reason for this revved-up invasiveness, researchers concluded from experiments done in mice, is that drugs like Avastin increase the portion of a tumor made of breast cancer stem cells.
Although Avastin, when initially given, causes some cancer cells to die and tumors to shrink, what's left behind are the cancer stem cells, according to the study. These cells can then multiply, and they are among the most lethal cancer cells ? they can sprout new tumors more easily than run-of-the-mill cancer cells.
The finding suggests that clinicians could improve Avastin's effectiveness by blocking this unwanted effect of the drug. It's a potentially bright spot for the drug, after a November decision by the Food and Drug Administration that the drug should not be used to treat breast cancer?after studies showed the drug failed to lengthen patient's lives.
"This result explains why they don't work as well as we hoped it would, and it really points to what we need to do to develop drug combinations that are more effective," said Dr. Max Wicha, author of the new study and an oncologist at the University of Michigan.
The new findings, which may also apply to other drugs in the same class as Avastin, were published Monday (Jan. 23) in Proceedings of the National Academy of Sciences.
The seeds of a tumor
Avastin falls into a category of cancer drugs called antiangiogenic agents, which aim to work by blocking the growth of blood vessels that supply tumors with vital nutrients and oxygen. Without a blood supply, tumors will die, the thinking goes.
"There was a lot of excitement about using these drugs to block the blood supply to tumors," Wicha said. "But the first large studies showed that while Avastin seemed to be preventing tumors from progressing for a few months, the tumors would then start to grow again, and be even more aggressive."
Wicha said he and his colleagues suspected the cause of the new, aggressive growth, might be cancer stem cells. "These cells are the most dangerous, if they're left in the body," he explained. "They're like the seeds of a plant."
The researchers tested their theory by giving an antiangiogenic drug to mice with breast cancer tumors. As expected, the tumors shrank and had fewer blood vessels feeding them. When the team analyzed the cells within the tumors, however, the tumors of mice that had been treated with an antiangiogenic drug had five times more stem cells.
Further, the scientists found, the lack of oxygen ? called hypoxia ? in the tissues that followed the death of the blood vessels had the side effect of encouraging the growth of these dangerous cells. If doctors could combine drugs that kill the cancer stem cells with antiangiogenic drugs, they may have a winning formula, Wicha said.
"Our research suggests that it's going to necessary to target both angles of this at the same time," he said.
Two sides of a drug
The new findings didn't surprise Celeste Simon, a molecular biologist at the University of Pennsylvania School of Medicine who studies the role of the body's low oxygen environments to human health.?
"Stem cells really like to reside in a low oxygen area," Simon said.
What the study adds, Simon said, is evidence that drugs like Avastin increase the pool of cancer stem cells living in these low-oxygen conditions.
"The notion is that by making the tumor more hypoxic, you're actually selecting for the more aggressive cells," she said. "This and other papers underscore a growing idea in the therapeutic world that, like all treatments, antiangiogenic drugs need to be very carefully evaluated in terms of their full impact on human health."
But more work is needed, she said, to flesh out the full molecular details of the observation. Tumors implanted into mice, such as the study used, aren't always a perfect mimic of human biology. "While these results are intriguing, they need to be followed up, from my point of view, with experiments on more sophisticated mouse models or primary tumors," Simon said.
Pass it on: ?Although Avastin successfully cuts off the blood supply of breast cancer tumors, it also increases the number of so-called breast cancer stem cells that can lead to tumor growth in the long run.
This story was provided by MyHealthNewsDaily, a sister site to LiveScience. Follow MyHealthNewsDaily on Twitter @MyHealth_MHND. ?Find us on?Facebook.
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Thursday, January 26, 2012
Fran Drescher Launches 'Trash Cancer' Website - Starpulse.com
The former The Nanny star, who survived uterine cancer, has launched the Trash Cancer website to help consumers become familiar with toxins found in skincare, food and cleaning agents.
The site also features survivors' stories, healthy recipes and government petitions to ban carcinogens.
In a video clip, Drescher explains, "We have to start thinking about the products that we clean our home with that we put on our skin and what we put into our mouths. There are so many toxins that we expose ourselves to that are now being linked to many different health issues like infertility, developmental issues and, of course, cancer."
?
"You can start to recognize what chemicals are on the 'iffy' list, what chemicals are considered carcinogens... so you can make better, more informed decisions for you and your family. We want to live a preventative lifestyle, find out what the causes of cancer are and eliminate them.
?
"If given the choice and you have some education and information, you may choose one product over another. Just become an educated consumer, be a medical consumer. Learn the early warning whispers of the cancers that might affect you, and the tests that are available."
Source: http://www.starpulse.com/news/index.php/2012/01/26/fran_drescher_launches_trash_cancer_we
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UFC on Fox 2?s Mike Russow balances police work and fighting
While putting together a record of 14-1 with three wins in the UFC, Russow has kept his day job in the Chicago Police Department. Russow currently patrols the third district on the city's South Side. He is understandably hesitant to give specifics about the details of his daily work,? but said that he has been recognized as a fighter when on the job.
"I had someone who I was arresting for a warrant, and he saw the Chicago Sun-Times picture that day. He noticed," Russow said.
Though Russow can't use his Octagon-worthy moves on offenders, he says police work and fighting share a mental side.
"You have to be calm. There's a lot of situations with police work where it's scary. You're clearing a house, by yourself, it's dark, no lights, and you don't know if the offender is in there. It's just like in the cage."
His calm demeanor came in handy when Russow fought Todd Duffee at UFC 114.
"When I was fighting Todd Duffee, he was beating my ass. I stayed calm, hung in there, and got a lucky punch. I think that's how it helps. Being mentally tough."
He broke his left arm early in the bout, and was having trouble with his right arm. Still he knew he had to pull something out to get the win.
"It was like an effortless punch. The right technique, and the right time, and I hit him and he went down. I was coming off of elbow surgery, and I couldn't extend my right arm all the way. My left arm broke. I knew something was wrong. Right before that I thought, I got to do something."
After beating Duffee, Russow TKOed Jon Madsen. Those wins earned him a shot at Einemo, a highly decorated grappler. Because of Einemo's ground skills, Russow hopes to keep the fight standing.
"I've really worked a lot on my stand-up game. He's a world-class jiu jitsu guy, so even if I did get the takedown, I don't know if I want to play in his world. I'm more or less going to try and control him and keep it standing."
To prepare for this bout, Russow used up all of his vacation time and spent time just training. Most UFC-level fighters train full-time, and Russow was appreciative of the chance to focus on MMA. He said he would love the chance to fight full time, but it's not a practical option.
Unlike UFC welterweight Sean Pierson, who was not allowed to join the Toronto Police Department because of his fight career, the CPD has been supportive of Russow.
"I've never had any problems. My bosses have been really supportive. I've been fortunate. They think it's a little nuts, but they support it."
Balancing the two careers is not easy. Since he works from 5 p.m. to 2 a.m., his sleep and diet are both disrupted.
"Every time you go to a gas station, they try to give you something, take this, take that. Not that I do, but it makes it harder. And you get hungry anyways around 10 or 11. I wish I was in bed, but I'm stuck out there working."
But this Saturday, when his friends, family, and fellow police officers fill the United Center with cheers, Russow will be living a dream. He'll be fighting in the Octagon in the city he patrols. It's a far cry from the days he had to sit outside the United Center, waiting for the Bulls game to end.
"Back then, I never would have imagined this."
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